Laboratory Response Network

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LRN: Protecting the Nation from Health Threats

The LRN provides rapid detection of biological, chemical, radiological and other public health threats.


The Laboratory Response Network (LRN) is the nation's laboratory emergency response system. It tests for agents of biological and chemical terrorism, emerging infectious diseases, and other public health threats, for example, from natural disasters. Founded by APHL, CDC and the FBI in 1999 to improve US readiness for bioterrorism, the LRN remains a valuable resource for law enforcement and public health, providing unprecedented linking of laboratories. State and local public health laboratories form the backbone of the LRN Network.

APHL supports the LRN through training of laboratorians, quality improvement initiatives, surge capacity and exercise planning, policy development and fostering of partnerships.

The LRN for Biological Terrorism Preparedness utilizes a tiered construct of sentinel clinical, reference and national laboratories as an integrated network for rapid detection and response to threats. State and local public health, clinical, federal, military, veterinary, agricultural, environmental and international laboratories all participate.