*Starting June 3, 2013, this course will be hosted by the Centers for Disease Control. Please note by clicking the registration link above you will be redirected from APHL website to the Centers for Disease Control Training Program website. You will need to follow the registration prompts including creating an account on the CDC TRAIN portal. Help can be obtained by sending an email to or by calling 404-498-6022.


Each of these Intermediate-level, interactive online course modules review a component of the Laboratory Response Network (LRN) protocols for bioterrorism agent identification. The modules include case studies, real-life laboratory scenarios and links to resource information. Course materials may be used as part of a laboratory’s competency assessment program for terrorism preparedness. Updated for 2013; six course modules are available, including: 

  • Anthrax (Bacillus anthracis)
  • Brucella (Brucella spp)
  • Burkholderia (Burkholderia spp)
  • Plague (Yersinia pestis)
  • Tularemia (Francisella tularensis)
  • Laboratory Biosecurity



These online course modules are designed for public health and clinical laboratorians, safety professionals and persons interested in the laboratory’s role in bioterrorism preparedness.


After completion of all modules, the participant will be able to:
Define the levels of the Laboratory Response Network (LRN) and discuss their relationship with each other

  • List potential bioterrorism agents that must be reported to public health authorities, and explain the role of the clinical laboratory in detecting these organisms in clinical specimens.
  • Discuss standardized laboratory tests used to isolate and identify Bacillus anthracis, Brucella spp, Burkholderia spp, Yersinia pestis, Francisella tularensis, and explain how to use these tests to rule out or refer isolates.
  • Define biosecurity, including threats, vulnerabilities and relationship to biosafety
    Explain how to conduct a laboratory biosecurity risk assessment and use the results to formulate a complete biosecurity plan.
  • Identify appropriate reference resources. 
  • Continuing Education

    Participants who successfully complete each module of this course will be awarded 1.5 contact hours, or a total 9.0 contact hours for all modules. Application to the ASCLS P.A.C.E.® Program has been submitted.  If you have further questions please contact

    Delivery Format

    Program is best viewed using Windows XP and Internet Explorer 6.x and 7.x. Windows Vista users should use Internet Explorer 7.x. NOTE: Pop-up blockers must be turned off.

    The course modules each include a pre-test, post-test and evaluation, all of which need to be completed in order to receive continuing education credit.